Evaluation of Spleen Stiffness-Spleen Size-to-Platelet Ratio Score (SSPS) as Non-Invasive Predictor of Oesophageal Varices in Patients with Cirrhosis of Liver
نویسندگان
چکیده
Background and Aim: Early diagnosis evaluation of oesophageal varices (OV) in cirrhosis liver is crucial before the first variceal bleeding as it associated with high mortality. As upper GI endoscopy (UGIE) has limitations like being invasive poor patient compliance, non-invasive methods that can be used for OV needs to evaluated. Both LSM SSM predict but are having varied sensitivity specificity. By combining spleen size platelet count (LSPS), predicting improved. There only one study till date which evaluated combination SS (SSPS) a predictor OV. Hence this was aimed evaluate SSPS presence severity Methods: This prospective cross-sectional conducted at KIMS, Bhubaneswar from April 2021 March 2023. 132 consecutive patients compensated any etiology were included. Clinical evaluations, laboratory investigations, abdominal ultrasonography, UGIE FibroScan done. other markers APRI, FIB 4, PSR, LSPS calculated. Results: Mean age 52.5 years males 80.3 %. Most common alcohol (68.9%). OVs present 52.3% cases among them, 45% had large varices. Compared all (LSM, SSM, FIB-4, APRI LSPS) studied, found most accurate both (AUROC 0.997, 97.1, specificity 98.41% accuracy 97.7%) grading (AUROC, 0.941, 93.55, 86.14 89.5%.) Conclusion: good diagnosing hence screening test
منابع مشابه
Liver stiffness-spleen size-to-platelet ratio risk score detects esophageal varices in chronic liver disease
BACKGROUND Noninvasive markers are needed to identify esophageal varices (EV) in patients with chronic liver disease (CLD). Recently, liver stiffness (LS)-spleen size-to-platelet ratio risk score (LSPS) has been shown to predict EV in patients with chronic hepatitis C. The aim of this study was to validate the clinical value of LSPS for EV detection and identification of high risk EV in Japanes...
متن کاملPlatelet count/spleen diameter ratio as a predictor of oesophageal varices in alcoholic cirrhosis.
متن کامل
Platelet count/spleen diameter ratio: proposal and validation of a non-invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosis.
BACKGROUND AND AIMS Cirrhotic patients frequently undergo screening endoscopy for the presence of oesophageal varices (OV). In the future, this social and medical burden will increase due to the greater number of patients with chronic liver disease and their improved survival. In this study, our aims were (1) to identify clinical, biochemical, and ultrasonographic parameters which might non-inv...
متن کاملPlatelet Count to Spleen Diameter Ratio and to Spleen Area Ratio as Predictors for Esopha-geal Varices in Chronic Hepatitis C Patients with Liver Cirrhosis.
Endoscopic detection of esophageal varices (EV) especially the high risk esophageal varices (HREV) is recommended in cirrhotic patients. There are several studies about non-invasive markers to predict the presence of EV. The aim of this study was to evaluate platelet count to spleen diameter (P/D) ratio and platelet count to spleen area (P/A) ratio as predictors for EV and HREV in patients with...
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ژورنال
عنوان ژورنال: Journal of clinical and experimental hepatology
سال: 2023
ISSN: ['0973-6883', '2213-3453']
DOI: https://doi.org/10.1016/j.jceh.2023.07.309